Pancreatic secretory testing in 1974.

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Pancreatic secretory testing in 1974.

bicarbonate response to various acids in duodenum of the dog. Amer. J. Physiol., 219,964-970. Mfeyer, J. H., Way, L. W., and Grossman, M. I. (1970b). Pancreatic response to acidification of various lengths of proximal intestine in the dog. Amer. J. Physiol., 219, 971-977. Novis, B. H., Bank, S., and Marks, I. N. (1971). The cephalic phase of pancreatic secretion in man. Scand. J. Gastroent., 6,...

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Intracellular Transport of Secretory Proteins in the Pancreatic Exocrine Cell

Since in the pancreatic exocrine cell synthesis and intracellular transport of secretory proteins can be uncoupled (1), it is possible to examine separately the metabolic requirements of the latter process. To this intent, guinea pig pancreatic slices were pulse labeled with leucine-(3)H for 3 min and incubated post-pulse for 37 min in chase medium containing 5 x 10(-4)M cycloheximide and inhib...

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Immunocytochemical localization of secretory proteins in bovine pancreatic exocrine cells

The bovine exocrine pancreatic cell produces a variety of enzymes and proenzymes for export. Biochemical studies by Greene L.J., C.H. Hirs, and G.E. Palade (J. Biol. Chem. 1963. 238:2054) have shown that the mass proportions of several of these proteins in resting pancreatic juice and zymogen granule fractions are identical. In this study we have used immunocytochemical techniques at the electr...

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Control of secretory granule interaction and exocytosis in pancreatic cells.

Application of the laser-based technique of photon correlation spectroscopy to an in vitro study of the ionic stability and interaction kinetics of zymogen granules isolated from rat exocrine pancreas is described here. In addition the separation from pancreatic acinar cell cytosol of a factor which stabilizes isolated zymogen granules and inhibits cation-induced granule aggregation is outlined...

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Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice.

We studied the distribution of pancreatic secretory trypsin inhibitor (PSTI) in the epithelia of the gastrointestinal tract and determined whether PSTI is secreted into gastric juice. PSTI was measured by a specific radioimmunoassay in biopsy specimens taken from the upper (n = 8) and lower (n = 7) gastrointestinal tract of patients with normal endoscopies. PSTI was present in the stomach, smal...

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ژورنال

عنوان ژورنال: Gut

سال: 1975

ISSN: 0017-5749

DOI: 10.1136/gut.16.8.653